ii4sm - Semantic Interoperability Platform, Drug Safety Application, Modeling &Simulation Tools

Providers, payers, pharmaceutical companies, regulators and other healthcare and life science stakeholders increasingly need to exchange large amounts of data about treatments, outcomes, payments and analytical results in order to improve cost effective quality healthcare.

Where other industries such as manufacturing, telecommunications and banking streamlined these electronic communications during the last 20 years, healthcare data integration has remained largely a manual process. Extracting data from isolated sources and not having the ability to access information in its context is a major limiting factor for medical interpretation. The healthcare sector is poised to transform the way information is managed and ii4sm is committed to support and help drive this transformation with an innovative semantic interoperability platform and cutting edge, domain-specific applications.

ii4sm’s patent-pending information platform will facilitate meaningful healthcare data analysis in a scalable and unambiguous form through Computable Semantic Interoperability (CSI). ii4sm’s proprietary technology was developed building on lessons learned from the implementation of interoperability principles within the Cancer Biomedical Informatics Grid (caBIG) of the U.S. National Cancer Institute (NCI).

The first ii4sm software application is a disruptive drug safety solution that will revolutionize the pharmacovigilance sector, facilitating an open and transparent process, involving multiple stakeholders, allowing post-marketing to be shared for more meaningful analyses and improving the way modern companies and institutions act in complex collaborative environments.

Other healthcare applications on ii4sm’s interoperability platform are being planned with strategic partners and clients.

Additionally, ii4sm is offering modeling & simulation tools for quality information exchange and overall pharmacovigilance process optimization.

The ii4sm Computable Semantic Interoperability platform is characterized by:

  • Unambiguous data exchange based on semantic interoperability, maintaining the context of the data
  • Delivery / SaaS (Software as a Service) - fully Internet-based hosting for remote access and / or access behind the company’s firewall
  • Extension / SOA (Service Oriented Architecture) - easy development of healthcare applications for flexible and cost-efficient deployment and configuration of client solutions
  • Quality / standards and terminologies for healthcare and life sciences are included (new ones can be added) and processes can be tailored, maximizing the return on investment within dynamically changing environments


ii4sm collaborates with leading pharmaceutical companies, healthcare and IT partners, academic institutions and standard setting bodies to define standards, develop best practices and refine data provisioning & analytic methods.

For more information about licensing or partnering opportunities, please send us a mail to This e-mail address is being protected from spambots. You need JavaScript enabled to view it or use our contact form.